Antigenic Characterization of Polish Infectious Bursal Disease Virus Strains
نویسندگان
چکیده
Antigen Capture-ELISA based on eight different neutralizing mouse monoclonal antibodies (Mabs) was used to study Polish infectious bursal disease viruses (IBDVs) isolated from two epidemics on the turn of 70/80s (early IBDV) and in the 90s (recent IBDV). They were compared to the Faragher 52/70 (F52/70) reference strain of European classical serotype 1 IBDV and to the 89/163 (typical) and 91/168 (atypical) French very virulent (vv) IBDV isolates. All Polish viruses, irrespective of the isolation date, exhibited antigenic profile which was different from the F52/70 reference strain (no binding of Mabs 3 and 4). Two of the early IBDVs did not react with Mab 5 and two of six recent IBDV did not react with Mab 8. The other recent Polish viruses had an antigenic reactivity similar to that of typical vvIBDV.
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